: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
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Instead of making antibodies, the cancer cells make proteins that don't work and cause symptoms like bone pain. Kimberlee Speakman, PEOPLE, 4 July 2026 The researchers behind the new study suggest such alpha-gal antibody surveillance data can help identify areas with high prevalence ripe for further research. Beth Mole, ArsTechnica, 7 July 2026 The proof of concept arrived in 2021, when the company showed its antibody restored teeth in mice born without them due to a gene deficiency affecting dental development. Allison Palmer, Sacbee.com, 6 July 2026 The antibodies bind to the virus’s surface glycoprotein, preventing it from entering human cells while also recruiting the immune system to eliminate infected cells. Omer Awan, Forbes.com, 7 July 2026 See All Example Sentences for antibody

Word History

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

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Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 10 Jul. 2026.

Kids Definition

: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

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