cyclization

noun

cy·​cli·​za·​tion ˌsī-k(ə-)lə-ˈzā-shən How to pronounce cyclization (audio)
ˌsi-
: formation of a ring in a chemical compound
cyclize
ˈsī-kə-ˌlīz How to pronounce cyclization (audio) ˈsi- How to pronounce cyclization (audio)
-ˌklīz
verb

Examples of cyclization in a Sentence

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Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Because the design pipeline, built on 3D modeling, cyclization and amino acid substitution, can in principle be pointed at many disease targets, success in one therapeutic area tends to pull investment into adjacent ones. — Samantha Agate, Kansas City Star, 16 Oct. 2026

Word History

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of cyclization was in 1909

Rhymes for cyclization

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Browse Nearby Words

cyclitol
cyclization
cyclized rubber
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Cite this Entry

“Cyclization.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cyclization. Accessed 27 Oct. 2026.

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Medical Definition

cyclization

noun
cy·​cli·​za·​tion
variants or British cyclisation
ˌsīk-(ə-)lə-ˈzā-shən, ˌsik- How to pronounce cyclization (audio)
: formation of one or more rings in a chemical compound

More from Merriam-Webster on cyclization

Britannica.com: Encyclopedia article about cyclization

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