: any of a group of triglyceride-lowering drugs (such as gemfibrozil) that are derivatives of clofibrate

Word History

First Known Use

1983, in the meaning defined above

Time Traveler
The first known use of fibrate was in 1983

Browse Nearby Words

Cite this Entry

“Fibrate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fibrate. Accessed 7 Jul. 2026.

Medical Definition

: any of a group of triglyceride-lowering drugs (such as fenofibrate and gemfibrozil) that are derivatives of clofibrate
… we conclude that the benefit of adding a fibrate to statin therapy in reducing the risk of cardiovascular events in patients with type 2 diabetes remains unproven.Allison B. Goldfine et al., The New England Journal of Medicine
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!