1
a
: a small anatomical cavity or deep narrow-mouthed depression
b
: a small lymph node
c
: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells
especially : graafian follicle
2
: a dry dehiscent one-celled many-seeded fruit (as of the milkweed) that has a single carpel and opens along one suture

Examples of follicle in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Minoxidil prolongs the growth phase of those follicles. Allison Palmer, Kansas City Star, 22 June 2026 It’ll eventually be pushed out by a new follicle underneath in the telogen phase, and the process repeats itself. Alanna Martine Kilkeary, Glamour, 17 June 2026 After several months, the old hair is shed, the follicle reactivates and a new anagen cycle begins. Scott Travers, Forbes.com, 29 June 2026 Minoxidil improves blood flow to follicles and must be used indefinitely to maintain results. Allison Palmer, Miami Herald, 22 June 2026 See All Example Sentences for follicle

Word History

Etymology

New Latin folliculus, from Latin, diminutive of follis bag — more at fool

First Known Use

1715, in the meaning defined at sense 1a

Time Traveler
The first known use of follicle was in 1715

Browse Nearby Words

Cite this Entry

“Follicle.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/follicle. Accessed 7 Jul. 2026.

Kids Definition

follicle

noun
1
a
: a small cavity or a deep bodily depression with a narrow mouth (as one from which a hair grows)
2
: a dry one-celled fruit (as in the milkweed) that splits open by one seam when ripe

Medical Definition

follicle

noun
1
: a small anatomical cavity or deep narrow-mouthed depression
especially : a small simple or slightly branched gland : crypt
2
: a small lymph node
3
: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells : ovarian follicle
especially : graafian follicle

More from Merriam-Webster on follicle

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!