hydrochloride

noun

hy·​dro·​chlo·​ride ˌhī-drə-ˈklȯr-ˌīd How to pronounce hydrochloride (audio)
: a chemical complex composed of an organic base (such as an alkaloid) in association with hydrogen chloride

Examples of hydrochloride in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The bag allegedly included oxycodone hydrochloride and acetaminophen, which prosecutors say Sorrell did not have a valid prescription for. — Paula Wethington, CBS News, 26 Mar. 2026 Each antihistamine tablet is formulated with 10 milligrams of cetirizine hydrochloride to help reduce hives and relieve itching due to hives. — Adam Mills, MSNBC Newsweek, 10 Sep. 2025 The agency also cleared an early-stage clinical trial for noribogaine hydrochloride, a derivative of ibogaine, as a potential treatment for alcohol use disorder. — Brandon Gomez, CNBC, 24 Apr. 2026 But in 2021, the FDA approved a breakthrough eye drop treatment called Vuity, which uses pilocarpine hydrochloride to stimulate the pupil to contract. — Andrew Paul, Popular Science, 7 Aug. 2025 See All Example Sentences for hydrochloride

Word History

First Known Use

1826, in the meaning defined above

Time Traveler
The first known use of hydrochloride was in 1826

Phrases Containing hydrochloride

Rhymes for hydrochloride

See All Rhymes for hydrochloride

Browse Nearby Words

hydrochloric acid
hydrochloride
hydrochlorinate
See all Nearby Words

Cite this Entry

“Hydrochloride.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydrochloride. Accessed 7 Jul. 2026.

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Medical Definition

hydrochloride

noun
hy·​dro·​chlo·​ride -ˈklō(ə)r-ˌīd, -ˈklȯ(ə)r- How to pronounce hydrochloride (audio)
: a salt of hydrochloric acid with an organic base used especially as a vehicle for the administration of a drug
Last Updated: - Updated example sentences
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