: the molecular structure and conformation of an antibody that confers its antigenic specificity

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of idiotype was in 1967

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Cite this Entry

“Idiotype.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/idiotype. Accessed 7 Jul. 2026.

Medical Definition

: the molecular structure and conformation in the variable region of an immunoglobulin that confers its antigenic specificity compare allotype, isotype
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