: the labeling of antibodies or antigens with fluorescent dyes especially for the purpose of demonstrating the presence of a particular antigen or antibody in a tissue preparation or smear
immunofluorescent adjective

Examples of immunofluorescence in a Sentence

Recent Examples on the Web
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Or, a healthcare provider may use an immunofluorescence assay. Health Editorial Team, Health, 21 Apr. 2023 This was also paired with immunofluorescence microscopy, which uses antibodies linked to fluorescent dyes to tag specific proteins or cells. Melissa Cristina Márquez, Forbes.com, 11 July 2025 Another type of quick influenza test known as an immunofluorescence assay has similar reliability problems. Elizabeth Svoboda, Scientific American, 18 Sep. 2019 This multicolor immunofluorescence image shows human endothelial cells being infected by cytomegalovirus. Discover Magazine, 29 June 2010 Common testing methods include reverse transcription polymerase chain reaction, viral culture and immunofluorescence assays. Sacbee.com, 23 Jan. 2026 First, a sensitive enzyme immunoassay (EIA) or immunofluorescence assay (IFA), both of which look for the presence of antibodies, or proteins the immune system produces in response to an antigen (a foreign substance in the body, such as a virus). Kate Fridkis, SELF, 14 Apr. 2021

Word History

Etymology

immuno- + fluorescence

First Known Use

1960, in the meaning defined above

Time Traveler
The first known use of immunofluorescence was in 1960

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Cite this Entry

“Immunofluorescence.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immunofluorescence. Accessed 7 Jul. 2026.

Medical Definition

: the labeling of antibodies or antigens with fluorescent dyes especially for the purpose of demonstrating the presence of a particular antigen or antibody in a tissue preparation or smear
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