: a nucleoside C10H12N4O5 that is composed of hypoxanthine and ribose, that in the form of its monophosphate is a biosynthetic precursor of both AMP and its guanosine analog, and that binds to adenine, cytosine, or uracil especially in some transfer RNAs

Examples of inosine in a Sentence

Recent Examples on the Web
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Although not one of the canonical RNA bases, inosine is read by the cell’s protein-translation machinery as the familiar guanosine. Sara Reardon, Scientific American, 5 Feb. 2020 As Bass and a colleague discovered in the late 1980s, cells often replace one building block in their mRNA molecules, adenosine, with another molecule known as inosine. Bymitch Leslie, science.org, 24 Oct. 2024

Word History

Etymology

International Scientific Vocabulary inosinic acid (the acid C10H13N4O8P; inosinic, from Greek in-, is sinew + International Scientific Vocabulary -ose entry 2 + -in entry 1 + -ic entry 1) + -ine entry 2

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of inosine was in 1911

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Cite this Entry

“Inosine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/inosine. Accessed 8 Jul. 2026.

Medical Definition

: a crystalline nucleoside C10H12N4O5 that is composed of hypoxanthine and ribose, that in the form of its monophosphate is a biosynthetic precursor of both AMP and its guanosine analog, and that binds to adenine, cytosine, or uracil especially in some transfer RNAs
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