monosomic

adjective

mono·​so·​mic ˌmä-nə-ˈsō-mik How to pronounce monosomic (audio)
: having one less than the diploid number of chromosomes
monosomic noun
monosomy
ˈmä-nə-ˌsō-mē How to pronounce monosomic (audio)
noun

Word History

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of monosomic was in 1926

Rhymes for monosomic

See All Rhymes for monosomic

Browse Nearby Words

monosome
monosomic
monospecific
See all Nearby Words

Cite this Entry

“Monosomic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/monosomic. Accessed 7 Jul. 2026.

Copy Citation

Medical Definition

monosomic

1 of 2 adjective
mono·​so·​mic ˌmän-ə-ˈsō-mik How to pronounce monosomic (audio)
: having one less than the diploid number of chromosomes
monosomy
ˈmän-ə-ˌsō-mē How to pronounce monosomic (audio)
noun
plural monosomies
autosomal monosomy

monosomic

2 of 2 noun
: a monosomic individual
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Popular in Grammar & Usage

See More

Is that lie 'bald-faced' or 'bold-faced'?

'A' or 'an'? What about before 'h'? An Indefinite Article Guide

Why is '-ed' sometimes pronounced at the end of a word?

Commonly Misspelled Words

How to Use Em Dashes (—), En Dashes (–) , and Hyphens (-)
See More

Popular in Wordplay

See More

14 Phobias You Probably Haven't Heard Of

The Longest Long Words List

One-Word Oxymorons: Bittersweet, Spendthrift, and More

Ten Words Ending with a Silent ‘T’

12 Lovely and Unusual Words for the Natural World
See More

Popular

See More

Is that lie 'bald-faced' or 'bold-faced'?

14 Phobias You Probably Haven't Heard Of

The Longest Long Words List
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
hangman letters and game
Hangman Lightning Round Figure out which word fits in the blanks.
See All