Adjective
some people find a glass of wine to be a civilized and sedative addition to an evening meal Noun
The patient was given a powerful sedative.
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Adjective
Ambien, or zolpidem, acts on GABA-A receptors in the central nervous system to produce a sedative effect, states FDA prescribing information.—
Angelica Stabile,
FOXNews.com,
23 Oct. 2026 While one form, or isomer, of thalidomide has a sedative effect, the other is thought to cause abnormal physiological development.—
Sajish Mathew,
The Conversation,
7 Oct. 2026
Noun
The analysis suggested melatonin could offer advantages over traditional sedatives for older adults, who may be more susceptible to confusion after surgery.—
Angelica Stabile,
FOXNews.com,
23 Oct. 2026 Others cite potential sharp shifts in drug use behaviors, such as people stopping opioid use because the supply became less desirable through lacing with sedatives such as xylazine and medetomidine.—
J. Travis Donahoe,
STAT,
23 Oct. 2026 See All Example Sentences for sedative
Word History
Etymology
Adjective
Middle English, alleviating pain, from Middle French sedatif, from Medieval Latin sedativus, from Latin sedatus