: highly potent marijuana from female plants that are specially tended and kept seedless by preventing pollination in order to induce a high resin content
also : a female hemp plant grown to produce sinsemilla

Word History

Etymology

American Spanish, from sin without + semilla seed

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of sinsemilla was in 1975

Browse Nearby Words

Cite this Entry

“Sinsemilla.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sinsemilla. Accessed 7 Jul. 2026.

Medical Definition

: highly potent marijuana from female plants that are specially tended and kept seedless by preventing pollination in order to induce a high resin content
also : a female hemp plant grown to produce sinsemilla
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