Synonyms of syndromenext
1
: a group of signs and symptoms that occur together and characterize a particular abnormality or condition
2
: a set of concurrent things (such as emotions or actions) that usually form an identifiable pattern

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Combining its two Greek roots, syndrome means basically "running together". So when diagnosing a condition or disease, doctors tend to look for a group of symptoms existing together. As long as a set of symptoms remains mysterious, it may be referred to as a specific syndrome. But if that name is used for a while, it may become the condition's permanent name, even after an underlying cause has been found. So today we have Down syndrome, acquired immune deficiency syndrome, Asperger's syndrome, carpal tunnel syndrome, chronic fatigue syndrome, Tourette's syndrome, sick building syndrome, and many more. And since mental conditions often turn out to have physical causes, syndrome is used in psychology as well as in medicine.

Examples of syndrome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Abigail Bailey spent most of her life thinking Tourette syndrome had taken away her future. Gabby Sartori, USA Today, 3 July 2026 Alpha-gal syndrome is caused by ticks, usually the lone star tick, that have previously fed on mammals like cows, deer, goats and pigs. Erika Edwards, NBC news, 2 July 2026 Chevalier, who is also the mother of a daughter with Down syndrome, added that Gudiel's curriculum fills an important gap. Toria Sheffield, PEOPLE, 5 July 2026 Madden died in 2014 from complications of myelodysplastic syndrome. Will Harris, Entertainment Weekly, 6 July 2026 See All Example Sentences for syndrome

Word History

Etymology

New Latin, from Greek syndromē combination, syndrome, from syn- + dramein to run — more at dromedary

First Known Use

1541, in the meaning defined at sense 1

Time Traveler
The first known use of syndrome was in 1541

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Cite this Entry

“Syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/syndrome. Accessed 7 Jul. 2026.

Kids Definition

: a group of signs and symptoms that occur together and characterize a particular abnormality or condition

Medical Definition

syndrome

noun
syn·​drome
ˈsin-ˌdrōm also -drəm
: a group of signs and symptoms that occur together and characterize a particular abnormality

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