Synonyms of syndromenext
1
: a group of signs and symptoms that occur together and characterize a particular abnormality or condition
2
: a set of concurrent things (such as emotions or actions) that usually form an identifiable pattern

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Combining its two Greek roots, syndrome means basically "running together". So when diagnosing a condition or disease, doctors tend to look for a group of symptoms existing together. As long as a set of symptoms remains mysterious, it may be referred to as a specific syndrome. But if that name is used for a while, it may become the condition's permanent name, even after an underlying cause has been found. So today we have Down syndrome, acquired immune deficiency syndrome, Asperger's syndrome, carpal tunnel syndrome, chronic fatigue syndrome, Tourette's syndrome, sick building syndrome, and many more. And since mental conditions often turn out to have physical causes, syndrome is used in psychology as well as in medicine.

Examples of syndrome in a Sentence

Recent Examples on the Web
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Known as oral allergy syndrome, this cross-reaction can cause symptoms such as itching or tingling in the mouth. — Lauren Finney Harden, AJC.com, 20 Oct. 2026 Schumer, who previously revealed she had been diagnosed with Cushing syndrome, explained that her health had been a major factor in her physical transformation. — Danielle Minnetian, FOXNews.com, 20 Oct. 2026 To get this to work, the system had to take the syndrome data obtained from querying the measurement qubits and figure out the nature of any errors that were detected. — ArsTechnica, 20 Oct. 2026 There is a real-life medical condition called Capgras syndrome, a disorder that can be triggered by a brain injury where a person believes that someone close to them has been replaced by an impostor. — Maira Garcia, Los Angeles Times, 20 Oct. 2026 See All Example Sentences for syndrome

Word History

Etymology

New Latin, from Greek syndromē combination, syndrome, from syn- + dramein to run — more at dromedary

First Known Use

1541, in the meaning defined at sense 1

Time Traveler
The first known use of syndrome was in 1541

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Cite this Entry

“Syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/syndrome. Accessed 28 Oct. 2026.

Kids Definition

: a group of signs and symptoms that occur together and characterize a particular abnormality or condition

Medical Definition

syndrome

noun
syn·​drome
ˈsin-ˌdrōm also -drəm
: a group of signs and symptoms that occur together and characterize a particular abnormality

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