vaccinate

verb

vac·​ci·​nate ˈvak-sə-ˌnāt How to pronounce vaccinate (audio)
vaccinated; vaccinating

transitive verb

: to administer a vaccine to usually by injection

intransitive verb

: to perform or practice vaccination
vaccinator
ˈvak-sə-ˌnā-tər How to pronounce vaccinate (audio)
noun

Examples of vaccinate in a Sentence

We vaccinate all the animals that come to our shelter.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In Tarrant County, the vaccination rate for the measles-mumps-rubella vaccine has dropped in the last year, from almost 94% of kindergartners vaccinated to almost 93% vaccinated. — Ciara McCarthy, Fort Worth Star-Telegram, 20 Oct. 2026 Risky infection Pregnant people who have not been vaccinated against measles nor previously had the infection are susceptible. — Beth Mole, ArsTechnica, 19 Oct. 2026 Health experts are also pushing the government to expand the program to vaccinate children over 5. — Reuters, NBC news, 19 Oct. 2026 Checks cover everything from ensuring fridges are available for keeping vaccines cool to determining how many children should be vaccinated. — Arkansas Online, 18 Oct. 2026 See All Example Sentences for vaccinate

Word History

Etymology

earlier, "to inoculate with fluid from a cowpox pustule," back-formation from vaccination; in later extended sense, in part borrowed from French vacciner, verbal derivative of vaccin vaccine

First Known Use

1882, in the meaning defined at transitive sense

Time Traveler
The first known use of vaccinate was in 1882

Browse Nearby Words

vaccinal
vaccinate
vaccination
See all Nearby Words

Cite this Entry

“Vaccinate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/vaccinate. Accessed 27 Oct. 2026.

Copy Citation

Kids Definition

vaccinate

verb
vac·​ci·​nate ˈvak-sə-ˌnāt How to pronounce vaccinate (audio)
vaccinated; vaccinating
: to give a vaccine to usually by injection
vaccinator
-ˌnāt-ər How to pronounce vaccinate (audio)
noun

Medical Definition

vaccinate

1 of 2 verb
vac·​ci·​nate ˈvak-sə-ˌnāt How to pronounce vaccinate (audio)
vaccinated; vaccinating

transitive verb

1
: to inoculate (a person) with cowpox virus in order to produce immunity to smallpox
2
: to administer a vaccine to usually by injection

intransitive verb

: to perform or practice vaccination
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Last Updated: - Updated example sentences

More from Merriam-Webster

Word of the Day

Listen to the pronunciation of milieu

See Definitions and Examples »

Popular in Grammar & Usage

See More

How to Use 'Who' vs. 'Whom'

Merriam-Webster’s Great Big List of Words You Love to Hate

'Affect' vs. 'Effect'

'A' or 'an'? What about before 'h'? An Indefinite Article Guide

Why is '-ed' sometimes pronounced at the end of a word?
See More

Popular in Wordplay

See More

The Longest Long Words List

9 Words That Sound Like Insults But Aren't

12 Lovely and Unusual Words for the Natural World

Why do we 'bury the lede?'

'Za' and 9 Other Words to Help You Win at SCRABBLE
See More

Popular

See More

How to Use 'Who' vs. 'Whom'

The Longest Long Words List

9 Words That Sound Like Insults But Aren't
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
different halloween monsters in silhouette
A Monstrous Vocab Quiz Words That Go Bump in the Night
See All