vicissitude

noun

vi·​cis·​si·​tude və-ˈsi-sə-ˌtüd How to pronounce vicissitude (audio)
vī-
-ˌtyüd
Synonyms of vicissitude
1
a
: the quality or state of being changeable : mutability
b
: natural change or mutation visible in nature or in human affairs
2
a
: a favorable or unfavorable event or situation that occurs by chance : a fluctuation of state or condition
the vicissitudes of daily life
b
: a difficulty or hardship attendant on a way of life, a career, or a course of action and usually beyond one's control
c
: alternating change : succession

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Changes and Vicissitude

"Change is not made without inconvenience, even from worse to better," wrote British theologian Richard Hooker in the 16th century. That observation may shed some light on vicissitude, a word that can refer simply to the fact of change, or to an instance of it, but that often refers specifically to hardship or difficulty brought about by change. To survive "the vicissitudes of life" is thus to survive life's ups and downs, with special emphasis on the downs. Vicissitude is a descendant of the Latin noun vicis, meaning "change" or "alternation," and it has been a part of the English language since the 16th century. In contemporary usage, it most often occurs in the plural.

Examples of vicissitude in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Their vicissitudes are both timely and for all time. Peter Rainer, Christian Science Monitor, 17 Dec. 2025 The show is good at making the off-and-on vicissitudes of modern dating feel natural to the plot. Doreen St. Félix, New Yorker, 14 Feb. 2026 By using non-actors who have endured the vicissitudes of the world, Laxe didn’t have to develop the characters in a conventional way. Anne Thompson, IndieWire, 12 Nov. 2025 Renaissance has prided itself on a debt-free history, despite the vicissitudes of performing arts fundraising. Jim Higgins, jsonline.com, 24 Sep. 2025 See All Example Sentences for vicissitude

Word History

Etymology

Middle French, from Latin vicissitudo, from vicissim in turn, from vicis change, alternation — more at week

First Known Use

circa 1576, in the meaning defined at sense 1a

Time Traveler
The first known use of vicissitude was circa 1576

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Cite this Entry

“Vicissitude.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/vicissitude. Accessed 7 Jul. 2026.

Kids Definition

vicissitude

noun
: a surprising or irregular change

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