: any of several diseases of humans and domestic animals usually marked by severe gastrointestinal symptoms
especially : an acute diarrheal disease caused by an enterotoxin produced by a comma-shaped gram-negative bacillus (Vibrio cholerae synonym V. comma) when it is present in large numbers in the proximal (see proximal sense 2) part of the human small intestine

Examples of cholera in a Sentence

Recent Examples on the Web
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Kirsten’s best friend dies of cholera within the first few chapters. Clare Mulroy, USA Today, 3 July 2026 Floods, for example, often trigger outbreaks of diseases like cholera. Maryanne Murray Buechner, Forbes.com, 2 July 2026 As a result, deaths from cholera, dysentery and typhoid fever fell dramatically. Melissa Rudy, FOXNews.com, 3 July 2026 Ibn Sori died of cholera shortly after gaining his freedom, and at least seven of his children remained enslaved in Mississippi. Leila Tarakji, The Conversation, 17 June 2026 See All Example Sentences for cholera

Word History

Etymology

borrowed from Latin, "acute gastroenteritis," borrowed from Greek choléra — more at choler

First Known Use

1601, in the meaning defined above

Time Traveler
The first known use of cholera was in 1601

Browse Nearby Words

Cite this Entry

“Cholera.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cholera. Accessed 8 Jul. 2026.

Kids Definition

: any of several diseases usually marked by severe vomiting and diarrhea

Medical Definition

: any of several diseases of humans and domestic animals usually marked by severe gastrointestinal symptoms: as
a
: an acute diarrheal disease caused by an enterotoxin produced by various strains of a comma-shaped gram-negative bacterium of the genus Vibrio (V. cholerae) when it is present in large numbers in the proximal part of the human small intestine see asiatic cholera

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