connective tissue

noun

: a tissue of mesodermal origin that consists of various cells (such as fibroblasts and macrophages) and interlacing protein fibers (as of collagen) embedded in a chiefly carbohydrate ground substance, that supports, ensheathes, and binds together other tissues, and that includes loose and dense forms (such as adipose tissue, tendons, ligaments, and aponeuroses) and specialized forms (such as cartilage and bone)

Examples of connective tissue in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Estrogen also plays a role in joint and connective tissue health, immune activity, and inflammation, so related pain tends to worsen during hormonal shifts. — Cheyenne Buckingham, Washington Post, 24 Oct. 2026 The connective tissue between different models remains immature, and real transformation depends on it. — Chris Koehler, Fortune, 23 Oct. 2026 The connective tissue, according to sources, is the amoral android played by Michael Fassbender. — Borys Kit, HollywoodReporter, 23 Oct. 2026 Food director Chris Morocco recommends cooking dark meat to an even higher final temperature—around 175°F–190°F—so its connective tissue has more time to break down. — Julie Harans, Bon Appetit Magazine, 22 Oct. 2026 See All Example Sentences for connective tissue

Word History

First Known Use

1846, in the meaning defined above

Time Traveler
The first known use of connective tissue was in 1846

Rhymes for connective tissue

See All Rhymes for connective tissue

Browse Nearby Words

connective
connective tissue
connectivity
See all Nearby Words

Cite this Entry

“Connective tissue.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/connective%20tissue. Accessed 31 Oct. 2026.

Copy Citation

Kids Definition

connective tissue

noun
: a tissue (as bone, cartilage, or tendon) that forms a supporting framework for the body or its parts and has protein fibers between the cells composing it

Medical Definition

connective tissue

noun
con·​nec·​tive tissue kə-ˌnek-tiv- How to pronounce connective tissue (audio)
: a tissue of mesodermal origin that consists of various cells (as fibroblasts and macrophages) and interlacing protein fibers (as of collagen) embedded in a chiefly carbohydrate ground substance, that supports, ensheathes, and binds together other tissues, and that includes loose and dense forms (as adipose tissue, tendons, ligaments, and aponeuroses) and specialized forms (as cartilage and bone)

More from Merriam-Webster on connective tissue

Britannica.com: Encyclopedia article about connective tissue

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Last Updated: - Updated example sentences

More from Merriam-Webster

Word of the Day

Listen to the pronunciation of wraith

See Definitions and Examples »

Popular in Grammar & Usage

See More

How to Use 'Who' vs. 'Whom'

Merriam-Webster’s Great Big List of Words You Love to Hate

'Affect' vs. 'Effect'

'A' or 'an'? What about before 'h'? An Indefinite Article Guide

Why is '-ed' sometimes pronounced at the end of a word?
See More

Popular in Wordplay

See More

The Longest Long Words List

9 Words That Sound Like Insults But Aren't

Pwn, Skibidi, Girlboss and Other Words Added to the 2026 Scrabble Dictionary

The Words of the Week - Oct. 30

12 Lovely and Unusual Words for the Natural World
See More

Popular

See More

How to Use 'Who' vs. 'Whom'

The Longest Long Words List

9 Words That Sound Like Insults But Aren't
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
different halloween monsters in silhouette
A Monstrous Vocab Quiz Words That Go Bump in the Night
See All