1
medical : of, relating to, or affected with hypoxia : resulting from, causing, or experiencing inadequate levels of oxygen in the tissues and cells of the body
hypoxic cells
She was then transferred to Tufts Medical Center with hypokalemia, hyperglycemia, and hypoxic ischemic encephalopathy—abnormal brain function from oxygen deprivation—and seizures.Rebecca Everett
At altitudes up to ten thousand feet, the mild hypoxic effects encountered do not materially deteriorate our flying ability …Joseph W. Benkert
The Australian looks slightly hypoxic, as if he is finding the atmosphere up here in the Northern Hemisphere a trifle thin.Craig S. Karpel
2
: characterized by reduced levels of dissolved oxygen
Hypoxic conditions, which occur when dissolved oxygen concentrations are less than 2 mg/L, can cause stress or death in bottom-dwelling organisms that cannot leave the zone.Donald A. Goolsby
Also, the loss of herbivorous cichlids has contributed to colossal algae blooms in the lake, which suck oxygen from the water and create huge hypoxic zones.Mark Jerome Walters

Examples of hypoxic in a Sentence

Recent Examples on the Web
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Kalani has hypoxic-ischemic encephalopathy, a form of brain injury that affects muscle tone and mobility. Eva Remijan-Toba, Chicago Tribune, 10 Jan. 2026 Some go to hypoxic altitude hotels, like the Syncrosfera in Dénia, Spain, favoured by Mathieu van der Poel. Chris Marshall-Bell, New York Times, 29 June 2026 Ladd died of hypoxic respiratory failure, according to her death certificate, obtained by People. Theresa Braine, Mercury News, 1 Dec. 2025 According to a death certificate obtained by People, Ladd died as a result of acute on chronic hypoxic respiratory failure, a condition where the lungs cannot provide enough oxygen to the blood. Denise Petski, Deadline, 17 Nov. 2025 See All Example Sentences for hypoxic

Word History

First Known Use

1942, in the meaning defined at sense 1

Time Traveler
The first known use of hypoxic was in 1942

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Cite this Entry

“Hypoxic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hypoxic. Accessed 7 Jul. 2026.

Medical Definition

hypoxic

adjective
: of, relating to, or affected with hypoxia : resulting from, causing, or experiencing inadequate levels of oxygen in the tissues and cells of the body
To date, several forms of hypoxic training and/or altitude exposure exist. … Although substantial differences exist between these types of hypoxic training and/or exposure, all have the same primary goal: to induce an improvement in athletic performance at sea level. These methods are also used for preparation for competition at altitude or for the acclimatization of mountaineers.Gregoire P. Millet et al., Sports Med
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