1
: spot, blotch
especially : macule
2
a
: an anatomical structure having the form of a spot differentiated from surrounding tissues
b
: a small yellowish area lying slightly lateral to the center of the retina that is made up mostly of cones (see cone entry 1 sense 3a), plays a key role in visual acuity, and has the fovea at its center

called also macula lutea, yellow spot

Examples of macula in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The antioxidants build up in the macula, which is the part of your eye that controls sharp, central vision. Lindsay Curtis, Health, 12 Nov. 2025 The macula, the central part of the retina, is responsible for sharp vision. Emily Kay Votruba, EverydayHealth.com, 28 Oct. 2025 The condition develops when fluid builds up in the macula — the central portion of the retina at the back of the eye, where vision is sharpest. Samantha Agate, Charlotte Observer, 1 May 2026 The macula, part of the retina needed for sharp vision, may become distorted, causing blurry sight. Liz Szabo, Scientific American, 14 Oct. 2025 See All Example Sentences for macula

Word History

Etymology

Middle English, borrowed from Latin, "stain, spot, blemish, one of the interstices of a net," of uncertain origin

Note: If macula goes back to *sma-tlā, then *sma- may represent an Indo-European base *smh1- seen in Greek smáō, smân "to cleanse, wipe clean," smêma "ointment."

First Known Use

15th century, in the meaning defined at sense 1

Time Traveler
The first known use of macula was in the 15th century

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Cite this Entry

“Macula.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/macula. Accessed 7 Jul. 2026.

Medical Definition

1
: a spot or blotch
especially : macule sense 2
2
: an anatomical structure having the form of a spot differentiated from surrounding tissues: as
b
: a small yellowish area lying slightly lateral to the center of the retina that is made up mostly of cones, plays a key role in visual acuity, and has the fovea at its center

called also macula lutea, yellow spot

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