How to Use X chromosome in a Sentence

X chromosome

noun
  • In some cases, the clones even lost an entire copy of their X chromosome.
    — Frank Landymore, Futurism, 26 Mar. 2026
  • With the most common types, the faulty gene is located on the X chromosome.
    — Beth Warren, The Tennessean, 21 Aug. 2025
  • In their view, men and boys have one X chromosome in their cells and one Y, which carries only a paltry set of genes.
    — Roxanne Khamsi, The Atlantic, 20 Sep. 2024
  • Those with two X chromosomes and ovaries lived longest, followed by mice with two X chromosomes and testes.
    — Mohana Ravindranath, New York Times, 25 Feb. 2025
  • While females have two X chromosomes, males have an X and Y chromosomes.
    — William A. Haseltine, Forbes, 13 Sep. 2024
  • As with other mammals, female cats have two X chromosomes, while males have one X and one Y.
    — Amanda Schupak, CNN Money, 23 May 2025
  • The absence of tusks is caused by a mutation in the X chromosome in elephants that is lethal to males, according to the study.
    — Washington Post, 22 Oct. 2021
  • Xist molecules work with those proteins to shut down gene expression in the second X chromosome.
    — Katie Hunt, CNN, 9 Feb. 2024
  • Typically, females have two X chromosomes while males have an X and a Y.
    — Viviane Callier, Scientific American, 3 Sep. 2024
  • Fragile X syndrome is a genetic disorder caused by a mutation in a gene that lies at the tip of the X chromosome.
    — Joel Richter, The Conversation, 26 July 2023
  • This signaled that the mutation was somewhere on the X chromosome, since females have two of those, and presumably one lacked the killer mutation.
    — Beth Mole, ArsTechnica, 6 Oct. 2025
  • Sasaki and his team decided to sequence the whole genomes of cats with different coat colors to single out any variations on the X chromosome.
    — Gayoung Lee, Scientific American, 15 May 2025
  • Two others formed their fingers into an X (to signify X chromosomes) after losing.
    — Mark Zeigler, The Mercury News, 12 Aug. 2024
  • Aicardi syndrome is an extremely rare condition that results from a mutation on the X chromosome.
    — Erika Edwards, NBC news, 4 Oct. 2025
  • Scientists have long hypothesized that women’s estrogen hormone and their double X chromosome may play a role in their longer lives.
    — Alexa Mikhail, Flow Space, 14 Jan. 2026
  • So far, no studies have proven a link among the X chromosome, immune response, and Covid-19 mortality rates.
    — Grace Huckins, Wired, 9 July 2020
  • Calico cats are overwhelmingly female, since two X chromosomes are required for their tri-color pattern.
    — Madeline Gunderson, USA Today, 5 July 2026
  • If a sperm cell carrying an X chromosome fertilizes the ovum, the fetus will be genetically female.
    — Heather Jones, Verywell Health, 19 Sep. 2024
  • The genetic analysis showed that some cells had one X chromosome and others had the usual two, known as mosaic Turner syndrome.
    — Elizabeth Rayne, Ars Technica, 15 Jan. 2024
  • None of these women manifested the traits of the disease, because the mutation occurred on one of their two X chromosomes, the other of which lacked the mutation.
    — Jerome Groopman, New Yorker, 6 Apr. 2026
  • Her research has found fascinating evidence of the benefits women may derive from their second X chromosome.
    — al, 16 Nov. 2021
  • To prevent the body from making too many of these proteins, one of the two X chromosomes in females is silenced in a process called X-chromosome inactivation.
    — Will Sullivan, Smithsonian Magazine, 5 Feb. 2024
  • Some research suggests that females might be protected from certain harmful genetic mutations because of the two X chromosomes.
    — Laura Baisas, Popular Science, 1 Oct. 2025
  • So if a genetic error on the X chromosome disrupts production of important proteins in the body, male patients suffer the consequence.
    — Roxanne Khamsi, The Atlantic, 20 Sep. 2024
  • The researchers discarded the Y chromosome and duplicated the X chromosome.
    — Meghan Bartels, Scientific American, 15 Mar. 2023
  • Dilute calicos are also typically female because the color genes are located on the X chromosome.
    — Michele Laufik, Martha Stewart, 10 June 2026
  • There’s less Neanderthal DNA on humans’ X chromosome than there is on most other chromosomes today.
    — Jackie Flynn Mogensen, Scientific American, 26 Feb. 2026
  • Women are twice as likely as men to develop these disorders because of the second X chromosome, which contains most genes involved in regulating the immune system.
    — Elizabeth Yuko, Flow Space, 30 Sep. 2025
  • The test, which identifies inactivated X chromosomes to determine an athlete’s chromosomal makeup, was done by a cheek swab.
    — Amy Woodyatt, CNN Money, 18 Sep. 2025
  • Chang’s team decided to engineer male lab mice to artificially make Xist — without silencing their only X chromosome — and see what happened.
    — TIME, 2 Feb. 2024

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'X chromosome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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