How to Use active site in a Sentence

active site

noun
  • Each enzyme has an active site, which is where the reaction takes place.
    — Svenja Lohner, Scientific American, 10 Nov. 2016
  • Many drugs are designed to fit into this active site, which can keep a protein from working.
    — John Timmer, Ars Technica, 25 Mar. 2022
  • The two churches were able to retain their names and will continue as active sites of the new parish.
    — Maryann Pisano, chicagotribune.com, 7 July 2018
  • Researchers believe this was all an active site roughly 7,000 years ago.
    — Tim Newcomb, Popular Mechanics, 11 May 2023
  • This method revealed five particular amino acids that comprise the likely active site.
    — Diana Gitig, Ars Technica, 20 Jan. 2018
  • Aubrey Valley/Double O Ranch is the only active site in the state.
    — Austin Corona, The Arizona Republic, 23 Sep. 2024
  • There were fewer than 50 active sites in August, shortly after the ban took effect.
    — Blake Nelson, San Diego Union-Tribune, 15 Jan. 2024
  • The researchers now plan to refine their maps further and hope future lunar missions will directly study these active sites.
    — Rupendra Brahambhatt, Interesting Engineering, 14 Sep. 2025
  • Including this project, Brasfield & Gorrie has four active sites in Cary.
    — William Thornton | [email protected], al, 21 Nov. 2019
  • There are multiple investigations still going on at the active site.
    — Mariah Rush, chicagotribune.com, 2 July 2021
  • The unique grooves in the enzyme – the lock – that interact with the target molecule – the key – are found in a region of the enzyme known as the active site.
    — Sam Pellock, The Conversation, 13 Feb. 2025
  • As the chain gets progressively longer, its ability to fit into the active site of the enzymes gradually gets worse.
    — John Timmer, Ars Technica, 20 Jan. 2020
  • There were no longer crowds outside the border wall gates marked 40 and 42 — some of the most active sites of migrant crossings recently.
    — Nick Miroff, Washington Post, 12 May 2023
  • Beyond its luminous core, Messier 77 is also a highly active site of star formation.
    — Bojan Stojkovski, Interesting Engineering, 10 May 2026
  • The fire was on private property owned by WR Grace, which isn’t an active site and went out of business, Arnum said.
    — Matt Yan, BostonGlobe.com, 23 May 2022
  • At these active sites, crop species experts evaluate, grow and distribute germplasm to researchers, professors and breeders worldwide.
    — Sena Christian, Newsweek, 19 Nov. 2015
  • Akaganeite gripped pollutants most strongly, but lepidocrocite had more chemically active sites that triggered faster bond breaking.
    — Neetika Walter, Interesting Engineering, 4 Nov. 2025
  • The first one reacts with the substrate surface at active sites, the points on the precursor molecules and on the surface of the substrate where the two materials chemically bond.
    — IEEE Spectrum, 12 Sep. 2024
  • The theory also hints at why results have been so inconsistent—creating enough active sites to produce meaningful amounts of heat requires nanoscale control over a metal’s shape.
    — Michael Koziol, IEEE Spectrum, 28 Nov. 2018
  • Errors affecting the enzyme’s active site that binds to drugs, however, can cripple its ability to break down a drug and subsequently mean there’s more of the drug circulating in the blood.
    — C. Michael White, The Conversation, 4 Oct. 2021
  • Researchers introduced a p–n heterojunction catalyst that combines graphitic carbon nitride with a carbon nanofiber network hosting dual cobalt active sites.
    — Prabhat Ranjan Mishra, Interesting Engineering, 6 Feb. 2026
  • The vineyard is an active site year-round, with pruning starting in January when vines are dormant (in the northern hemisphere) in anticipation of warmer weather and bud break in the early spring.
    — Mike Desimone and Jeff Jenssen, Robb Report, 5 Jan. 2023
  • At the detention center Alligator Alcatraz remained an active site the morning after Williams’ ruling.
    — Ana Ceballos, Miami Herald, 22 Aug. 2025
  • The nation’s active sites get an average of 8,700 requests to access their stocks annually, according to Peter Bretting, who oversees the system.
    — Sena Christian, Newsweek, 19 Nov. 2015
  • Despite 25 years of active site remediation, and evidence that the concentration of contaminants is declining, significant impacts to the soil and groundwater remain.
    — Staff Reports, Hartford Courant, 4 Jan. 2024
  • The location of the original Govan Old Parish Church was an active site of worship from the 5th century AD until 2007.
    — Leigh Anne Miller, ARTnews.com, 9 Apr. 2026
  • Instead of saturating or starving the active sites, this configuration supports a more optimal balance between how quickly reactants arrive and how efficiently they are converted, improving overall catalytic performance.
    — Bojan Stojkovski, Interesting Engineering, 3 May 2026
  • Subsequent studies report three drugs, boceprevir, narlaprevir, and telaprevir, inhibit NSP5 protease proteolytic activity and bind into its active site.
    — William A. Haseltine, Forbes, 4 June 2021

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'active site.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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