How to Use agonist in a Sentence

agonist

noun
  • For a long time, dopamine agonists were the first line of medications.
    — Madeline Holcombe, CNN Money, 11 June 2025
  • Centessa won’t be the first to market with its orexin agonist.
    — Angelica Peebles, CNBC, 31 Mar. 2026
  • At a certain point the dopamine agonist ropinirole was added to Les’s regimen.
    — Scott Sayare Robert Petkoff Anna Diamond Quinton Kamara, New York Times, 14 June 2024
  • The first is an inhaled bronchodilator (called a beta agonist), the same used in people with asthma.
    — Dr. Keith Roach, oregonlive, 6 Sep. 2022
  • The weight-loss products are called GLP-1 agonists.
    — NPR, 21 Nov. 2025
  • This is a form of medication known as a dual agonist, which works on two separate pathways.
    — Amber Smith, Discover Magazine, 21 Sep. 2023
  • Some men have had an increase in the blood pressure with mirabegron (the other available beta-3 agonist), so that is worth keeping an eye on.
    — Dr. Keith Roach, oregonlive, 30 June 2022
  • Methadone is a full-opioid agonist, and the restrictions are in place to prevent diversion of the substance.
    — Kerry Breen, CBS News, 17 Nov. 2022
  • The partisan agonists are not wrong about the significance of the moment.
    — Massimo Calabresi, Time, 28 June 2018
  • The third first-line treatment are inhaled steroids, almost always given with a long-acting beta agonist.
    — Dr. Keith Roach, oregonlive, 6 Sep. 2022
  • This is an issue that won’t go away anytime soon, at least not until the prices of GLP-1 agonists drop.
    — Bruce Y. Lee, Forbes, 21 Mar. 2025
  • Retatrutide is a triple agonist, adding glucagon for a metabolism boost.
    — Alexa Lomonaco, CNBC, 8 June 2026
  • But a new study found menopausal women may be able to find relief by taking tirzepatide, a GLP-1 agonist.
    — Helen Carefoot, Flow Space, 22 Dec. 2025
  • Another difference is that Zepbound is what's called a dual agonist drug.
    — Alexa Lomonaco, CNBC, 8 June 2026
  • One muscle — known as the agonist — contracts to move a limb and another — known as the antagonist — will lengthen in response.
    — Lizette Ortega, Washington Post, 1 July 2024
  • These are glucagon-like peptide-1 receptor agonists that imitate a natural hormone in the gut.
    — Stephanie Stephens, USA Today, 26 June 2026
  • Studies have showed the class of drugs, called GLP-1 agonists, work to suppress appetite and promote weight loss.
    — Ken Alltucker, USA TODAY, 4 Aug. 2023
  • GnRH agonists can only be used short-term because of the side effects, including permanent bone loss.
    — Meghan Cleary, Teen Vogue, 14 Sep. 2017
  • The doctor confirmed that the new drug, with its third receptor agonist, will further decrease hunger while increasing the feeling of fullness.
    — Angelica Stabile, FOXNews.com, 12 Jan. 2026
  • The class of drugs to which these four belong, called GLP-1 receptor agonists, is the reason for the special.
    — Daniel Engber, The Atlantic, 26 Mar. 2024
  • The apparent protective effect of dopamine agonist drugs could also be misleading.
    — Maria Morava, MSNBC Newsweek, 6 Oct. 2025
  • The pelvic muscle weakness may be due indirectly to the way GLP-1 agonists work.
    — Bruce Y. Lee, Forbes.com, 24 Aug. 2025
  • For those on the path to surgery, gonadotropin-releasing hormone (GnRH) agonists may be a better option.
    — Nick Blackmer, Verywell Health, 20 June 2023
  • New research shows the vast majority of people who try GLP-1 agonists for weight loss end up stopping them.
    — Mara Gordon, NPR, 24 Apr. 2025
  • This class of medication—known as beta-3 agonists—represents a newer approach to treatment.
    — Lauryn Higgins, Flow Space, 1 May 2026
  • The main kind of Kratom alkaloid, mitragynine, is a partial agonist for the mu-opioid signals [1].
    — Sponsored Content, The Mercury News, 19 Jan. 2024
  • Centrally acting alpha agonists help prevent the nervous system from responding to stress.
    — Jen Christensen, CNN Money, 30 Aug. 2025
  • But a class of drugs called GLP-1 agonists are revolutionizing the field.
    — Karen Weintraub, USA TODAY, 23 June 2023
  • And that's specifically caused by the GLP-1 agonists, and that's combined for diabetes and for weight loss.
    — Kristen Jordan Shamus, Detroit Free Press, 23 Feb. 2024
  • Phenibut functions as a GABA receptor agonist in the brain [2].
    — The Salt Lake Tribune, 15 Aug. 2023

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'agonist.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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