How to Use antidepressant in a Sentence

antidepressant

1 of 2 adjective
  • Pain meds and the antidepressant Lexapro let her function.
    — Gerald Witt, AJC.com, 1 Mar. 2026
  • The risk of suicide is the greatest during the first month of antidepressant treatment.
    — Dr. Yalda Safai, ABC News, 13 Apr. 2021
  • For years, middle-aged women have had some of the country’s highest rates of antidepressant use.
    — Andrea Petersen, WSJ, 2 Apr. 2022
  • One study found that icy temps help release endorphins, which could have an antidepressant effect.
    — Stephanie Dolgoff, Good Housekeeping, 9 Nov. 2022
  • Prior studies of the last 15 years have found that the drug might have antidepressant effects.
    — Kristen Rogers, CNN, 30 July 2020
  • Every commercial break in this game should be nothing but antidepressant ads.
    — J.j. Bailey, New York Times, 19 Oct. 2025
  • In this study, slow tapering was a gradual reduction in antidepressant dosage over the course of four weeks or more.
    — Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025
  • It is used as a dye, to enhance flavor in a variety of foods, for incense fragrance, and as an antidepressant tea.
    — Joshua Siskin, Oc Register, 25 Oct. 2025
  • But research on ketamine’s antidepressant effects has only taken off in the last couple decades.
    — Raleigh McElvery, Smithsonian Magazine, 24 May 2022
  • Other research has showed a massive increase in antidepressant use among youths who were exposed to local school shootings.
    — Washington Post, 3 Dec. 2021
  • That colossal figure is the value of the global antidepressant market.
    — Laura Newberry, Los Angeles Times, 25 Oct. 2022
  • In more than one letter, Diana makes rare comments to Stamp about the antidepressant Prozac.
    — Rachel Burchfield, InStyle, 9 June 2026
  • Many news stories used anecdotes and emphasized the risk of antidepressant use by children and adolescents.
    — Stephen B. Soumerai, STAT, 7 Jan. 2026
  • The test is supposed to measure depression in rats that are forced to swim in water, and it has been traditionally used to test antidepressant drugs.
    — Jude Zhu, Billboard, 4 Apr. 2022
  • Kombucha is packed with probiotics and the live microorganisms appear to have antidepressant effects.
    — Jodi Helmer, Fortune, 8 Nov. 2022
  • Each person had experienced at least two depressive episodes or had been on antidepressant medication for two years or more.
    — Sandee Lamotte, CNN, 30 Sep. 2021
  • The exam also turned up toxic levels of methamphetamine and the antidepressant Trazodone.
    — Carol Robinson | [email protected], al, 3 Oct. 2022
  • The fact that the antidepressant effect is so much larger than in facial feedback experiments is not cause for concern, Krüger says.
    — Cathleen O’Grady, Science | AAAS, 24 June 2021
  • Still, while most antidepressant dosages for pain management are too low to fully treat depressive symptoms, there may be some overlapping effects.
    — Claire Bugos, Verywell Health, 1 Mar. 2023
  • The drug at the heart of the story was derived from a popular antidepressant drug and approved as a treatment for stress fractures suffered by runners and triathletes.
    — Star Tribune, 8 Oct. 2020
  • Six months later, some participants reported that the antidepressant effects were still present.
    — Khloe Quill, FOXNews.com, 19 Feb. 2026
  • The research on ketamine, primarily used in the past as a horse tranquilizer, is the furthest along, and has been proven as an antidepressant treatment.
    — Ronit Molko, Forbes, 19 May 2022
  • Ramping up our positive feelings is key to managing our negative ones and pleasure can act like an antidepressant and anti-stress treatment.
    — Dr. Nan Wise, Glamour, 16 Aug. 2020
  • Anna — who was hospitalized and put on antidepressant medication — is now home, going to therapy and in a much better place.
    — Washington Post, 30 Mar. 2021
  • In Brazil, as in many countries, antidepressant use has risen as access to mental health care improves and more people (rightfully) receive support.
    — Melissa Cristina Márquez, Forbes.com, 2 July 2026
  • In addition, some of the alkaloids in red kratom can also increase serotonin and dopamine levels in the brain, providing antidepressant effects.
    — Dallas News, 10 Nov. 2022
  • Researchers found antidepressant effects from psilocybin and supportive psychotherapy may last at least a year in some patients.
    — Mary Kekatos, ABC News, 20 Apr. 2026
  • The antidepressant effects from these medications occur after weeks of treatment.
    — Joshua Cohen, Forbes, 3 Oct. 2022
  • Curcumin, the active ingredient that gives turmeric its yellow color, has been shown to have antidepressant effects.
    — Jodi Helmer, Fortune, 8 Nov. 2022
  • The antidepressant Paxil was linked to suicidal thoughts in adolescents (this link is still controversial).
    — Matthew Herper, STAT, 3 Nov. 2022

antidepressant

2 of 2 noun
  • The antidepressants treat their symptoms, rather than the cause, and could make things worse.
    — Laura Trujillo, USA Today, 19 Jan. 2026
  • Going on antidepressants can give many people their life back, but for some there is a catch.
    — Kristen Rogers, CNN Money, 12 Oct. 2025
  • On the other hand, the use of antidepressants and of gabapentin has increased.
    — Paula Span, Miami Herald, 25 Sep. 2025
  • About half took the antidepressant at home for 10 days, the rest got dummy pills.
    — NBC News, 27 Oct. 2021
  • But the risks that come with the trip are an obstacle to using the drugs as antidepressants.
    — Bycathleen O’Grady, science.org, 5 June 2023
  • Some were prescribed antidepressants that didn’t help.
    — Sarah Oreck, SELF, 2 Mar. 2026
  • The same is true for Pristiq, an antidepressant.
    — Nicholas Florko, The Atlantic, 6 Feb. 2026
  • Casiano said her doctor prescribed her with antidepressants, but nothing else.
    — Nadine El-Bawab, ABC News, 19 July 2023
  • As such, the rapid antidepressant increases serotonin in other parts of the brain.
    — Joshua Hawkins, BGR, 23 Nov. 2022
  • The highest antidepressant use was in moms who had parents or in-laws who were older, in poor health or living far away, the study showed.
    — Madeline Holcombe, CNN, 16 Feb. 2024
  • Trazodone is an antidepressant that is used off-label for insomnia.
    — Jessica Swirble, Verywell Health, 17 Sep. 2025
  • Patients and their doctors should work together to devise a plan to stop antidepressants.
    — Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025
  • She was even prescribed an antidepressant at age 9 and told that her struggles were the result of panic attacks.
    — Vanessa Etienne, PEOPLE, 5 Dec. 2025
  • But there is a patient movement calling for more research on the long-term effects of going off antidepressants.
    — Emily Kwong, NPR, 2 Sep. 2025
  • She was prescribed antidepressants But this mom was in menopause and needed another drug.
    — Laura Trujillo, USA Today, 4 Sep. 2025
  • Antacids, iron or calcium supplements and some antidepressants can have the same effect.
    — Daryl Austin, USA Today, 6 Sep. 2025
  • Pounding the pavement could be more effective than antidepressants, a recent study found.
    — Fox News Staff, Fox News, 11 Oct. 2023
  • The research looked at several ways of going off antidepressants.
    — Korin Miller, SELF, 12 Dec. 2025
  • Guilty for getting away not just without harm, but with a discipline that serves as an antidepressant and still carries me through hard times today.
    — Blair Glaser, Longreads, 25 Aug. 2022
  • However, the study didn't find much of a difference in dementia rates among those who took antidepressants.
    — Ken Alltucker, USA TODAY, 24 July 2023
  • That some antidepressants have black box warnings for suicidal thoughts and behaviors among youth is true, experts said.
    — Kristen Rogers, CNN Money, 4 Sep. 2025
  • Scientists don’t yet know how antidepressants work to minimize pain.
    — Claire Bugos, Verywell Health, 1 Mar. 2023
  • About halfway through the film, Ari and Liz talk about his decision to stop taking his antidepressants.
    — Hershal Pandya, Vulture, 8 Sep. 2025
  • Some antidepressants, bladder medications and pain pills can have the same effect.
    — Dr. Jamin Brahmbhatt, CNN Money, 15 Sep. 2025
  • The endorphins act as a mild pain reliever, whereas the serotonin is an antidepressant.
    — Cindy Gordon, Forbes, 14 Aug. 2022
  • Millions of people take antidepressants, and events being reported doesn’t always mean they’re linked to the drug.
    — Kristen Rogers, CNN Money, 4 Sep. 2025
  • However, talk to your healthcare provider first before changing your antidepressant dose.
    — Tolu Ajiboye, Verywell Health, 12 May 2023
  • Pop an ibuprofen or an antidepressant, and those levels will spike as the drug quickly passes through your gastrointestinal tract.
    — WIRED, 26 June 2023
  • The same argument has been made about antidepressants, which also work for many people for largely unknown reasons.
    — Laura Newberry, Los Angeles Times, 27 June 2023
  • The office identified the drugs as fentanyl and the antidepressant trazodone.
    — Emerson Clarridge, Fort Worth Star-Telegram, 13 Feb. 2024

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'antidepressant.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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