How to Use endocannabinoid in a Sentence
endocannabinoid
noun-
The endocannabinoid system triggers hunger when the body is low on resources.
—Matt Hrodey, Discover Magazine, 30 Apr. 2023
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Cannabinoids are found naturally in the brain in a non-psychoactive form called endocannabinoids.
—Shoshi Parks, Popular Science, 3 June 2026
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Cannabis is known to affect brain chemistry by interacting with the endocannabinoid system.
—Matt Rozo, Mercury News, 28 May 2025
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However, the team found endocannabinoid receptors in and around the blood-brain barrier.
—William A. Haseltine, Forbes, 25 Mar. 2025
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This hemp strain boasts a rich concentration of fatty acids, essential for the production of endocannabinoids in the body and brain.
—Amber Smith, Discover Magazine, 8 July 2023
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This is due to the fact that the endocannabinoid receptors in the body have a limit to how much they can be activated before becoming overwhelmed.
—Amber Smith, Discover Magazine, 24 Feb. 2023
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Delta 8 interacts with the body's endocannabinoid system, which plays a crucial role in maintaining balance.
—Amber Smith, Discover Magazine, 12 July 2023
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The endocannabinoid system, which controls a number of bodily processes, is made up of cannabinoid receptors that may be found all over the body.
—Amber Smith, Discover Magazine, 8 Dec. 2022
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Each person's body chemistry and endocannabinoid system are unique, meaning that what works for one individual may not work for another.
—Amber Smith, Discover Magazine, 13 Oct. 2023
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This small difference in the chemical structure affects the way the cannabinoid interacts with the body's endocannabinoid system.
—Amber Smith, Discover Magazine, 8 Sep. 2023
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Cannabinoids interact with the brain’s endocannabinoid system to reduce nausea and increase appetite.
—Tribune Content Agency, Mercury News, 2 June 2025
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As with any other cannabis product, results vary according to an individual’s unique endocannabinoid system.
—Tribune Content Agency, The Mercury News, 1 Oct. 2024
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These ingredients interact with receptors in the body’s endocannabinoid system, which plays a role in regulating mood, stress, and sleep-wake cycles.
—Tribune Content Agency, Mercury News, 28 Mar. 2025
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Those receptors normally respond to related molecules that are naturally present in the body, known as endocannabinoids.
—Katie Hunt, CNN, 20 Apr. 2023
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Instead, exercise triggers our bodies to release endocannabinoids, the endogenous cousin to cannabinoids, the stuff found in marijuana.
—Frederick Dreier, Outside, 11 Feb. 2026
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But there haven't been many studies of the endocannabinoid system in animals other than rodents and primates, especially invertebrates.
—Jennifer Ouellette, Ars Technica, 20 Apr. 2023
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Each of these variants interacts differently with your body’s endocannabinoid system, meaning each will affect you differently.
—Lydia Kariuki, The Mercury News, 2 Dec. 2024
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How Cannabis Works in the Body Cannabis interacts with the endocannabinoid system, which helps regulate functions like pain, mood, appetite, and sleep.
—Matt Rozo, Mercury News, 2 Apr. 2025
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This natural compound derived from the cannabis plant interacts with the endocannabinoid system, which plays a crucial role in regulating pain perception and immune response.
—Amber Smith, Discover Magazine, 5 Nov. 2023
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The same molecules in our brains that interact with THC (known as the endocannabinoid system) play an essential role in brain development.
—Carrie E. Bearden, Scientific American, 3 Feb. 2025
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The innumerable aspects of the still-mysterious human endocannabinoid system are mostly unknown, too.
—Nicholas Florko and Sarah Owermohle, STAT, 30 May 2024
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The body’s endocannabinoid system, which helps regulate mood, sleep, appetite and pain, interacts with the endocrine system, which produces and balances hormones like estrogen and progesterone.
—Lauryn Higgins, Flow Space, 30 June 2025
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Keep in mind that everyone’s body is different, and results may vary depending on your individual endocannabinoid system or condition being treated.
—Dallas News, 21 Dec. 2022
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Across vertebrate species, these molecules interact with the endocannabinoid system, a network of nerve receptors, molecules and enzymes that keeps the body’s other organ systems stable.
—Rachel Nuwer, New York Times, 6 Feb. 2024
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The former works to depress the central nervous system, temporarily putting your brain in chill mode while the liver metabolizes it; the latter conversely activates the endocannabinoid receptors in your brain.
—Ali Finney, SELF, 26 Feb. 2024
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Research increasingly reveals how cannabinoids interact with the body’s endocannabinoid system, which plays a critical role in regulating mood, appetite, sleep, and immune function.
—Amplified Content Studio, Mercury News, 15 Jan. 2026
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The chemicals can interact with the endocannabinoid system, a molecular network found throughout the body that supports homeostasis, or biological balance.
—Miriam Fauzia, Dallas Morning News, 4 Feb. 2026
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In this interaction with one's endocannabinoid system, the chemical compound works to calm one's nervous system, reduce inflammation and alleviate some chronic pain symptoms.
—Daryl Austin, USA TODAY, 8 June 2023
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These chemicals can interact with the endocannabinoid system, a molecular network found throughout the body that supports homeostasis, or biological balance.
—Tribune News Service, Baltimore Sun, 19 Feb. 2026
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These receptors form the endocannabinoid system, which acts as conductor for an orchestra of neurotransmitters, turning up or down the volume on sleep, temperature, pain, hunger, learning, and memory.
—Julia Michie Bruckner, Discover Magazine, 5 Apr. 2024
Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'endocannabinoid.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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