How to Use estradiol in a Sentence
estradiol
noun-
Sales of estradiol patches are up more than 200% from five years ago.
—Emma Hinchliffe, Fortune, 9 Feb. 2026
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The estradiol patch, a tiny square worn on the skin, may be discreet, but its impact is powerful.
—Jacqueline Howard, CNN Money, 23 Feb. 2026
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The reality is that men and women both have estradiol and testosterone.
—Tom Gavin, EverydayHealth.com, 23 Oct. 2025
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The prices for estradiol products for vaginal use have risen significantly over the past five years.
—Katie Thomas, New York Times, 3 June 2018
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The first patch that fell off had been on my butt, one of three permissible canvases for estradiol patches, the other two being abdomen and thigh.
—Nell Beram, Allure, 5 Feb. 2025
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For transgender women, this involves not only the use of estrogen (in the form of estradiol) but also the use of a testosterone blocker.
—Elizabeth Boskey, Verywell Health, 5 June 2023
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Women who had taken estradiol pills, on the other hand, had better test scores for prospective memory than nonusers of hormone therapy.
—Emily Kay Votruba, EverydayHealth.com, 27 Aug. 2025
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Some women may also consider a vaginal estradiol ring called Femring, says Cole.
—Tom Gavin, EverydayHealth.com, 26 Feb. 2026
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This formula also promotes a boost in free testosterone levels while reducing estradiol.
—Amber Smith, Discover Magazine, 12 June 2023
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Low levels of estradiol can point to PCOS or pituitary issues.
—Jennifer Gerson, Marie Claire, 1 Oct. 2018
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Testosterone and estradiol are dosed to meet physiologic targets rather than cosmetic goals.
—Jason Phillips, USA Today, 23 Aug. 2025
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The rat hole has been filled with coins and surrounded by offerings, including a shrine, handmade signs, gifts and even estradiol pills, which are estrogen hormones.
—Kat Tenbarge, NBC News, 24 Jan. 2024
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For example, being overweight or obese can lead to low testosterone and elevated estradiol, a form of the hormone estrogen.
—Karen Pallarito, Health, 12 May 2023
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One environmental estrogen is ethinyl estradiol—a chemical found in birth control pills.
—National Geographic, 3 Feb. 2016
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Women who are susceptible to migraines tend to experience a faster rate of estradiol decline around the time of their period compared to women who don’t.
—Lori Youmshajekian, WIRED, 23 Sep. 2024
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The key components are scientifically proved to raise testosterone levels and help battle estradiol.
—Amber Smith, Discover Magazine, 12 Oct. 2022
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Currently, estradiol monitoring requires blood or urine samples collected either in-clinic or at-home.
—Andrew Paul, Popular Science, 5 Oct. 2023
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Even more concerning, their estradiol levels — important for reproduction — were lower compared to females at non-feeding sites.
—Melissa Cristina Márquez, Forbes, 4 Mar. 2025
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In contrast, hormone therapy prescribed for menopause often involves higher doses of less potent estrogen—sometimes up to one milligram of estradiol.
—Lauryn Higgins, Flow Space, 19 Aug. 2025
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The resultant electrical signal can be wirelessly measured and correlated to estradiol levels via a simple-to-use smartphone app.
—Andrew Paul, Popular Science, 5 Oct. 2023
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Half of the participants will be given an estradiol patch for one week, while the other half will serve as a control group, and researchers will follow them to see whether estrogen reduces the severity of their disease.
—Roni Caryn Rabin, BostonGlobe.com, 27 Apr. 2020
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The study’s authors prescribed progesterone and estradiol, hormones that can influence lactation and that normally occur in pregnant women.
—Ceylan Yeginsu, New York Times, 15 Feb. 2018
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Manufacturers of estradiol patches have struggled to keep pace, creating supply disruptions at pharmacies across the country.
—Kristine Lazar, CBS News, 3 Mar. 2026
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Within three months, most of the transgender men’s testosterone levels entered the typical range for cisgender men while their estradiol (the most potent form of estrogen that is made in the body) and progesterone levels decreased.
—Tanya Lewis, Scientific American, 4 Sep. 2024
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Oral contraceptives used continuously prevent the large changes in progesterone and estradiol and may be helpful in managing perimenstrual asthma.
—Dr. Keith Roach, oregonlive, 4 Apr. 2023
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These receptors are found in multiple areas of the brain and are particularly important for mediating the cognitive and behavioral effects of estradiol, the most potent form of estrogen.
—Sandra Rose Salathe, Flow Space, 25 June 2024
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Estradiol blood test Secreted by maturing follicles, estradiol is a form of estrogen, the major female reproductive hormone.
—Jennifer Gerson, Marie Claire, 1 Oct. 2018
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Jorgensen enrolled in medical technician classes, managed to obtain the potent female hormone estradiol and began experimenting on herself.
—Francine Uenuma, Washington Post, 12 June 2023
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With further optimization, the new estradiol sensor could help users attempting to naturally or in vitro conceive children, as well as aid those necessitating hormone replacement therapies.
—Andrew Paul, Popular Science, 5 Oct. 2023
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But in endometriosis, the uterine lining is resistant to progesterone, and the competing hormone estradiol remains dominant, among other factors that make the environment less receptive to a blastocyst.
—Jena Pincott, Scientific American, 1 June 2018
Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'estradiol.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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