How to Use leptin in a Sentence

leptin

noun
  • The more fat on a person’s body, the more leptin is released.
    — Gina Kolata, New York Times, 22 July 2016
  • Higher levels of leptin in your bloodstream mean more fat on your body.
    — Jessica Migala, NBC News, 19 Sep. 2017
  • At the same time, leptin, the hormone that signals fullness, may plunge.
    — Samantha Lauriello, Health, 26 June 2023
  • So why did a drug to provide people with leptin never make it to market?
    — Judith Newman, New York Times, 28 Dec. 2016
  • At the same time levels of a hormone called leptin that tells the brain when the stomach is full plummet.
    — Sandee Lamotte, CNN, 23 Jan. 2025
  • So, their bodies were not relying solely on leptin to track and respond to weight changes.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • When your leptin levels are chronically high, your body resists it.
    — Rachael Zimlich, Bsn, Rn, Verywell Health, 10 July 2024
  • One of those cytokines is leptin, a satiety hormone secreted by fat tissue, which women tend to have more of than men.
    — Amanda MacMillan, Health.com, 1 Aug. 2017
  • The researchers next repeated the procedure, but in mice that had been bred to produce very little leptin.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • Not getting enough shut-eye also throws hunger and metabolism hormones like leptin and ghrelin out of whack.
    — Melissa Matthews, Men's Health, 10 Aug. 2023
  • Amgen bought the rights to leptin and, in 1996, began testing it in people.
    — Gina Kolata, New York Times, 17 Aug. 2023
  • In the longer term, the hypothalamus takes cues from an appetite-suppressant called leptin.
    — Cody Cottier, Discover Magazine, 8 Dec. 2023
  • Binge eating and restrictive diets could be causes for your leptin levels to be unbalanced.
    — Melanie Laughman, The Enquirer, 27 May 2023
  • This condition, known as leptin resistance, often plays a role in overeating and obesity.
    — Cody Cottier, Discover Magazine, 8 Dec. 2023
  • While this was exciting, more research did not support leptin as a big contributor to obesity.
    — Bryant Stamford, The Courier-Journal, 22 Mar. 2018
  • But that doesn’t work for people who have developed resistance to leptin, a hormone that suppresses appetite.
    — Karen Kaplan, Los Angeles Times, 15 Apr. 2024
  • Want to increase your leptin levels, suppress your appetite, and supercharge your metabolism around the clock?
    — Amber Smith, Discover Magazine, 3 Apr. 2024
  • Ghrelin, an appetite stimulant, rises when you are sleep-deprived, and leptin decreases.
    — Judy Stone, Forbes, 10 Mar. 2025
  • Some years ago, scientists did discover one of the likely mechanisms, which involves leptin, a hormone released by fat cells.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • Also implicated is the hormone leptin, which is released by fat cells and is responsible for feelings of satiety.
    — Jeffrey Kluger, Time, 6 Nov. 2019
  • As a result, leptin gets unblocked—sometimes in as little as a week, resulting in an end to ‘insatiable hunger’ and compulsive grazing.
    — Stephanie Walden, USA TODAY, 11 Jan. 2018
  • Their levels of the hormone leptin, which is responsible for feeling full, dropped, and the levels of the appetite- inducing hormone ghrelin went up.
    — Alexandra Sifferlin, Time, 1 May 2017
  • Also involved in the complex process are hormones, particularly the two that are often referred to as hunger hormones, leptin and ghrelin.
    — Amanda Gardner, PEOPLE.com, 19 Dec. 2017
  • It is also believed to reduce leptin levels in the body, which may additionally contribute to weight reduction.
    — Stephen C. George, Discover Magazine, 30 Apr. 2024
  • Consistently logging eight hours of sleep a night can help boost low testosterone levels and have a positive impact on cortisol, leptin and insulin levels.
    — Christy Brissette, Washington Post, 5 Aug. 2019
  • And mice with lots of leptin in their bloodstreams lost weight when given Celastrol, but the compound had no effect on mice with no leptin, or in mice without any leptin receptors.
    — K. N. Smith, Discover Magazine, 21 May 2015
  • The extra calories raise leptin production, a hormone that regulates appetite and energy.
    — Redbook, 26 July 2017
  • African Mango Extract helps to increase leptin levels, which can lead to a decrease in appetite and an increase in metabolism.
    — Discover Magazine, 29 Apr. 2023
  • As a result, the brain releases more of the hunger hormone ghrelin and dials down leptin, one of the hormones that signals fullness and energy sufficiency.
    — Amy J. Sheer, The Conversation, 5 Feb. 2026
  • The slow-rising blood glucose levels caused by low-GI foods help increase levels of the hormone leptin, which helps reduce food consumption at mealtimes.
    — New Atlas, 27 Oct. 2024

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'leptin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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