How to Use reuptake in a Sentence
reuptake
noun-
These drugs increase the levels of dopamine and norepinephrine in the brain by blocking their reuptake.
—Avery Hurt, Discover Magazine, 22 Mar. 2023
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Traditional selective serotonin reuptake inhibitors like Prozac can do the same thing, but that process could take months.
—Rene Chun, Los Angeles Magazine, 19 June 2017
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My mother was taking opiates for her pain and Trazodone, a serotonin reuptake inhibitor, to manage her bipolar syndrome, before the surgery.
—Winston Ross, Longreads, 8 Dec. 2019
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These also work to prevent the reuptake of GABA by neurons, prolonging the effect.
—Christie Wilcox, Scientific American, 1 May 2017
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Serotonin helps regulate mood, and drugs known as selective serotonin reuptake inhibitors are widely prescribed and effective for treating chronic depression.
—Quanta Magazine, 27 Oct. 2020
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The various selective serotonin-reuptake inhibitors used to treat depression offer a different challenge.
—The Economist, 14 Mar. 2020
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Specifically, Isaacson wonders about the long-term effects of her medication, a serotonin-norepinephrine reuptake inhibitor that is known to raise blood pressure.
—The New York Times News Service Syndicate, San Diego Union-Tribune, 27 Jan. 2026
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Another class, serotonin and norepinephrine reuptake inhibitors, came in the 1990s.
—Matt Richtel Annie Flanagan, New York Times, 27 Aug. 2022
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Currently, almost all patients with depression are first treated with medications called selective serotonin reuptake inhibitors, a class of drugs that includes both Zoloft and Prozac.
—Claudia López Lloreda, STAT, 17 Aug. 2021
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By blocking the reuptake of these neurotransmitters, duloxetine increases their levels in the brain, which helps regulate mood in conditions like depression and anxiety.
—Joseph Epstein, Newsweek, 10 Dec. 2024
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SSRIs work by blocking the brain’s reuptake of serotonin — a natural chemical that regulates bodily functions including mood.
—Laura Paddison, CNN, 2 Aug. 2024
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And then, in the late 1980s there’s the arrival of serotonin reuptake inhibitors, known as SSRIs, and their promise to be different from the antidepressants of the past.
—Maggie Jones, New York Times, 3 Apr. 2018
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Treatment typically involves selective serotonin reuptake inhibitors, or SSRIs, which boost levels of serotonin available to brain cells.
—Sandee Lamotte, CNN, 11 June 2022
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Much of the conversation around potential risks has centered on selective-serotonin reuptake inhibitors, which are known as SSRIs and are the most prescribed class of antidepressants.
—Kristen Rogers, CNN Money, 14 May 2026
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These drugs are mostly outdated and have been replaced with their more modern, less side-effect producing counterparts, like selective serotonin reuptake inhibitors, or SSRIs.
—Cori Ritchey, Men's Health, 19 Dec. 2022
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Since lower levels of serotonin are linked to sadness and depression, it is thought that by preventing the reuptake of serotonin, SSRIs fake higher overall serotonin levels and thus boost happy feelings.
—Christie Wilcox, Discover Magazine, 6 Oct. 2011
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There are plenty of antidepressants out there, but the most common are selective serotonin reuptake inhibitors (SSRIs), which can affect mood by increasing the amount of serotonin in the brain2.
—Ashley Abramson, SELF, 11 Feb. 2022
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Up to a third of people with the condition are still symptomatic 10 years after diagnosis, and the main therapeutic drugs of choice—the selective serotonin reuptake inhibitors sertraline and paroxetine—fail in up to 60% of patients.
—Jeffrey Kluger, Time, 11 May 2021
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Duloxetine is a prescription medication that belongs to the class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs).
—Paul Du Quenoy, Newsweek, 9 Dec. 2024
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In 1974, researchers developed the first serotonin reuptake inhibitor, or SSRI, intended to treat depression.
—Eleanor Cummins, The New Republic, 10 Aug. 2022
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In a new study, a group of scientists found that a selective serotonin reuptake inhibitors (SSRI) can affect reinforcement learning, which refers to a person’s decision-making abilities.
—Anuradha Varanasi, Forbes, 22 Jan. 2023
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Fluvoximine is a selective serotine-reuptake inhibitor that is typically prescribed to treat depression, social-anxiety disorder and obsessive-compulsive disorder.
—oregonlive, 30 Nov. 2021
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Duloxetine is a serotonin and norepinephrine reuptake inhibitor (SNRI).
—Mary Walrath-Holdridge, USA TODAY, 13 Dec. 2024
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Some benefit was found for another type of antidepressant — serotonin and norepinephrine reuptake inhibitors or SNRIs — but the researchers described the results as inconsistent.
—Linda Searing, Washington Post, 4 Sep. 2017
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Duloxetine belongs to the class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs) that help increase levels of serotonin and norepinephrine in the brain.
—Stephanie Brown, Verywell Health, 19 Dec. 2024
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Most were taking either a selective serotonin reuptake inhibitor (SSRI) or a serotonin and norepinephrine reuptake inhibitor (SNRI).
—Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025
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Wellbutrin, known generically as bupropion, is an aminoketone antidepressant or a dopamine reuptake inhibitor, whereas Adderall, known generically as dextroamphetamine/amphetamine is a central nervous system (CNS) stimulant.
—Bruce Y. Lee, Forbes, 30 Apr. 2022
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As the Mayo Clinic explains, Duloxetine is a type of selective serotonin and norepinephrine reuptake inhibitor (SSNRIs) which works by increasing serotonin and norepinephrine in the brain.
—Cara Lynn Shultz, PEOPLE, 15 June 2026
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Other medication classes, such as serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants or tricyclic antidepressants, may also be used depending on individual needs.
—Daryl Austin, USA Today, 14 Mar. 2026
Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'reuptake.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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