How to Use tumor necrosis factor in a Sentence

tumor necrosis factor

noun
  • The researchers injected some of the mice with the cytokines interleukin-1 beta and tumor necrosis factor.
    — Tim Hornyak, Scientific American, 10 May 2018
  • Furthermore, the agency has limited the drug’s use to patients who’ve tried but failed on at least one tumor necrosis factor inhibitor.
    — Trefis Team, Forbes, 7 Sep. 2021
  • One protein that stood out in the study was tumor necrosis factor alpha, which is made by the immune system to regulate inflammation.
    — Sandee Lamotte, CNN, 5 Apr. 2022
  • However, tumor necrosis factor alpha, another key response to acute injury that can also cause problems long term, did not change, the study found.
    — Sandee Lamotte, CNN, 12 Feb. 2020
  • Both of these drugs work by interfering with an immune system molecule called tumor necrosis factor, or TNF.
    — Markham Heid, Time, 10 Jan. 2023
  • These prevent the tumor necrosis factor protein from binding to its corresponding receptors and causing inflammation8.
    — Stephanie Watso, SELF, 27 Aug. 2021
  • The first generation of these drugs were TNF-alpha agents that targeted the tumor necrosis factor to limit the immune response.
    — Sun Pharmaceuticals, WIRED, 30 Oct. 2019
  • The researchers also hope to test an inhibitor of tumor necrosis factor, which is involved in inflammation, and another drug that inhibits the complement system, an arm of the immune system.
    — Kai Kupferschmidt, Science | AAAS, 3 Mar. 2021
  • In psoriasis, these overactive cells can lead to elevated levels of tumor necrosis factor, which is secreted via the inflammatory process.
    — Sun Pharmaceuticals, WIRED, 30 Oct. 2019
  • High levels of inflammatory markers like interleukin 6 and tumor necrosis factor inhibit the natural rhythm of the sleep-wake cycle, Wirth says.
    — Erin Prater, Fortune Well, 18 Mar. 2023
  • For example, your doctor might suggest an anti-tumor necrosis factor drug that blocks a protein called TNF-alpha that promotes inflammation.
    — Jennifer Larson, SELF, 3 Nov. 2021
  • This blocks the action of an inflammatory protein called tumor necrosis factor alpha (TNF alpha) in order to stop the immune system from attacking the colon wall.
    — Leah Schaffer, CNN, 19 Dec. 2017
  • Apart from a surge in interleukin-6, the body may also show high swirling levels of molecules called interleukin-1, interferon-gamma, C-reactive protein and tumor necrosis factor-alpha.
    — Apoorva Mandavilli, New York Times, 1 Apr. 2020
  • The liberation of tumor necrosis factor and immune-stimulating cytokines by metalloproteases and the release of bioactive lipids by phospholipases cause immune cells to rush to the wound.
    — Christie Wilcox, Discover Magazine, 19 Apr. 2016
  • The vaccine, according to the researchers, helps the body boost production of tumor necrosis factor, a hormone especially beneficial to Type 1 diabetics.
    — Fiza Pirani, ajc, 21 June 2018
  • Infliximab is an antibody given as a single infusion that blocks tumor necrosis factor alpha, a pivotal signaling molecule in the immune system, and is used to treat autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
    — Kai Kupferschmidt, Science | AAAS, 5 Aug. 2021
  • Many older people have increased concentrations of proinflammatory cytokines such as tumor necrosis factor (TNF), suggesting that a slight inflammatory state exists throughout the body at this point in life.
    — Kenneth S. Kosik, Scientific American, 20 Apr. 2020

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'tumor necrosis factor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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