LOCO Synonyms: 124 Similar and Opposite Words

loco 1 of 2

adjective

Definition of loco

slang

as in psychotic

unable to think in a clear or sensible way that dog's straight loco, just running around in circles all day long

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Antonyms & Near Antonyms

loco

2 of 2

verb

as in to bother

to cause to go insane or as if insane years of living alone had clearly locoed the old rancher

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Antonyms & Near Antonyms

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.

Recent Examples of loco

Adjective

Real investors survey the landscape and look for signs of a market gone loco. — Andy Kessler, WSJ, 2 July 2017

Recent Examples of Synonyms for loco

Adjective

Unfortunately, his doctor interprets all the screaming about an alien presence in Thomas’ head as a garden-variety psychotic breakdown, and remands him to a more secure facility.

— Tasha Robinson, Vulture, 14 Oct. 2026
It may also be used to treat certain other psychotic conditions, such as psychosis arising in Parkinson disease.

— Encyclopedia Britannica, Encyclopedia Britannica, 7 Oct. 2026

Definition of psychotic

Verb

The mathematics and computer science graduate, who spent two years in the Peace Corps, launched Netflix by mailing DVDs in red envelopes to customers bothered by Blockbuster Video chain’s practices and late fees.

— Meg James, Los Angeles Times, 26 Oct. 2026
Some people, like me, are bothered by such images but can mostly ignore them.

— Gabriela Galvin, Scientific American, 26 Oct. 2026

Definition of bother

Adjective

These three are just the latest in a mad rush for capital that has been putting a strain on the AI trade.

— Zev Fima, CNBC, 26 Oct. 2026
Both about power-mad blondes getting involved with the shadier side of the medical industrial complex, but Matt Hagen’s nanites worked, dammit!

— Bethy Squires, Vulture, 25 Oct. 2026

Definition of mad

Verb

Denying the Wave a crucial 1-0 lead, no teammate could convert on a bright drive and dish by speedster Ludmila that unbalanced Seattle’s defense.

— Tom Krasovic, San Diego Union-Tribune, 27 July 2026
The risk is that only a handful of clubs will be able to cough up those sums, unbalancing the market.

— Charlotte Harpur, New York Times, 19 May 2026

Definition of unbalance

Verb

From SheetsGate to purposefully washing Joy’s uniforms with rags, the laundry room has unleashed something deranged in Gen.

— Rafaela Bassili, Vulture, 22 Sep. 2026
Featuring an ensemble populated by killer character actors like Jacki Weaver, Luis Guzmán, Kurtwood Smith, Timothy Spall, and Michael Chernus, Perpetual Grace, LTD is an off-kilter neo-noir that mines deranged humor from its eccentric characters.

— Britt Hayes, Entertainment Weekly, 7 Aug. 2026

Definition of derange

Adjective

Rihanna’s here, maniacal crowds are lining up outside shows to screech and wave at their favorite stars and days of runway events big and small lie ahead.

— Leah Dolan, CNN Money, 30 Sep. 2026
These machines—the maniacal Maverick R, with its praying mantis-like front suspension, and the hard-working Pioneer—have little else in common.

— Caleb Jacobs, The Drive, 2 Sep. 2026

Definition of maniacal

Browse Nearby Words

lockups

loco

locoed

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Cite this Entry

Style

“Loco.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/loco. Accessed 28 Oct. 2026.

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Synonyms of loco

adjective

verb

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