: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate compare protein kinase

Examples of kinase in a Sentence

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When there’s no pathogen present, the two kinases are bound together — thus the handcuffs analogy. Paul Smaglik, Discover Magazine, 28 Mar. 2025 At the heart of rapamycin’s power lies its ability to inhibit a protein called the target of rapamycin kinase, or TOR. Ted Powers, The Conversation, 29 Sep. 2025 Previous research identified a problem protein, focal adhesion kinase, in several high-grade cases of ovarian cancer. Noah Lyons, San Diego Union-Tribune, 3 Apr. 2026 These cytokines travel through a pathway in the body known as the JAK-STAT pathway (short for Janus kinase–signal transducer and activator of transcription). Emily Kay Votruba, EverydayHealth.com, 1 Aug. 2025 See All Example Sentences for kinase

Word History

Etymology

International Scientific Vocabulary, from kinetic

First Known Use

1947, in the meaning defined above

Time Traveler
The first known use of kinase was in 1947

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Cite this Entry

“Kinase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/kinase. Accessed 7 Jul. 2026.

Medical Definition

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate

called also phosphokinase

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