How to Use kinase in a Sentence

kinase

noun
  • The key turned out to be a protein called a kinase, which attaches a phosphate to other proteins.
    — John Timmer, Ars Technica, 29 Mar. 2024
  • In more severe cases, some patients may use Janus kinase inhibitors.
    — NBC News, 7 Jan. 2022
  • Tanzi and his colleagues blocked a variety of different enzymes called kinases to try to stop the process.
    — Karen Weintraub, Scientific American, 16 Jan. 2020
  • One other type of drug, called a tyrosine kinase inhibitor, blocks an enzyme that’s needed for tumor cells to grow and divide.
    — Linda Carroll, TIME, 5 Sep. 2024
  • Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna.
    — WIRED, 4 Sep. 2023
  • Drugs called kinase inhibitors work by changing cellular function to fight itchiness.
    — Dr. Marty Becker and Kim Campbell Thornton, sacbee.com, 28 Apr. 2017
  • Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid.
    — Christine Coppa, Health, 15 Mar. 2023
  • Pyrukynd is a pill for a hereditary blood disorder called pyruvate kinase deficiency.
    — Globe Staff, BostonGlobe.com, 12 July 2022
  • The startup is developing drugs that rely on enzyme blockers known as kinase inhibitors to keep cancer cells from growing.
    — BostonGlobe.com, 29 July 2021
  • That signal involves the production of a type of cytokine called a Janus kinase, or JAK.
    — Marla Broadfoot, Scientific American, 1 Sep. 2021
  • The startup is developing lung cancer drugs that rely on enzyme blockers known as kinase inhibitors to help keep cancer cells from growing.
    — BostonGlobe.com, 14 May 2021
  • In the absence of this kinase (PLK1, for the curious), the three-protein complex doesn't form.
    — John Timmer, Ars Technica, 29 Mar. 2024
  • Among them was a compound called silmitasertib, which inhibits a kinase called CK2, and is being tested as a cancer drug.
    — Gregory Barber, Wired, 27 June 2020
  • The tests also look for whether the blood increases CaM kinase II activity.
    — Pamela Weintraub, Discover Magazine, 3 Jan. 2019
  • For his part, Hunter performed research that led to an entirely new category of cancer drugs called tyrosine kinase inhibitors.
    — San Diego Union-Tribune, 19 Aug. 2019
  • The class of cancer drugs that block phosphorylation activity are called tyrosine kinase inhibitors.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • The virus most powerfully hijacks a kinase called CK2, which plays a key role in the basic frame of the cell as well as its growth, proliferation and death.
    — Mark Johnson, Milwaukee Journal Sentinel, 27 June 2020
  • Given as a pill, mitapivat is designed to activate an enzyme called pyruvate kinase-R that red blood cells use to convert sugars into energy.
    — Adam Feuerstein, STAT, 18 Feb. 2022
  • Both monoclonal antibodies and tyrosine kinases now provide the basis for many new medicines coming to market.
    — Fred D. Ledley, STAT, 6 June 2018
  • Hunter made his reputation with the 1979 discovery of how enzymes called tyrosine kinases can cause cancer.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • The drug belongs to a large class of cancer drugs called tyrosine kinase inhibitors, the fruits of research by Tony Hunter at the Salk Institute four decades ago.
    — San Diego Union-Tribune, 17 Sep. 2019
  • Spectrum of discovery The Nature study can be viewed as an extension of Hunter’s groundbreaking work in tyrosine kinases.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • The tests were performed by virologists at Mount Sinai and the Institut Pasteur, who infected host cells with the virus and added the kinase inhibitors.
    — Jason Fagone, SFChronicle.com, 26 June 2020
  • In 1998 Druker started a clinical trial with his tyrosine kinase inhibitor.
    — Tony Dajer, Discover Magazine, 7 Feb. 2010
  • Zelboraf targets patients who test positive for a variant of the BRAF gene, another kinase that can go haywire and cause cells to grow out of control.
    — David Ewing Duncan, Discover Magazine, 30 Oct. 2012
  • Choanoflagellates have genes for tyrosine kinases, enzymes that, in complex animals, help control the functions of specialized cells, such as insulin secretion in the pancreas.
    — Elizabeth Pennisi, Science | AAAS, 28 June 2018
  • Other cancer therapies, such as a class of drugs known as Bruton's tyrosine kinase inhibitors, may be protective and are being tested in coronavirus patients without cancer.
    — Emily Woodruff, NOLA.com, 6 Aug. 2020
  • One pathway activates an enzyme called MAP kinase and is critical for metabolism and ovary development.
    — Viviane Callier, Quanta Magazine, 10 Jan. 2023
  • Previous research identified a problem protein, focal adhesion kinase, in several high-grade cases of ovarian cancer.
    — Noah Lyons, San Diego Union-Tribune, 3 Apr. 2026
  • But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250.
    — David Ewing Duncan, Discover Magazine, 30 Oct. 2012

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'kinase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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